• Profile picture of Dunja Aksentijevic
    Role: Other
    Affiliation(s): The Rayne Institute, BHF Centre of Research Excellence, Kings College London
    Research Summary:
    I am an associate lecturer in Cardiovascular Division at King's BHF Centre of Research Excellence with 8 years of cardiac metabolism scientific research experience (at the University of Oxford BHF Centre of Research Excellence, Prof Stefan Neubauer'... Read more
  • Profile picture of Jelle van den Ameele
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Neurosciences, MRC Mitochondrial Biology Unit
    Research Summary:
    Department of Clinical Neurosciences, MRC Mitochondrial Biology Unit
  • Profile picture of Professor Margaret Ashcroft
    Role: Principal Investigator
    Affiliation(s): Department of Medicine
    Research Summary:
    The main goal of the Ashcroft laboratory is to understand the key cellular mechanisms involved in hypoxia signalling and control of oxygenation. In particular, we have a strong interest in the hypoxia inducible factor (HIF) family of transcription fa... Read more
  • Profile picture of Irving Aye
    Role: Post Doctoral
    Affiliation(s): Obstetrics & Gynaecology
    Research Summary:
  • Profile picture of Miguel Constância
    Role: Principal Investigator
    Affiliation(s): Metabolic Research LaboratoriesDepartment of Obstetrics and Gynaecology
    Research Summary:
    Epigenetics is an exciting and rapidly moving field that impacts basic biomedical research and clinical medicine. Epigenetic mechanisms such as DNA methylation, histone modifications and non-coding RNAs provide dynamic, heritable and reversible ways ... Read more
  • Profile picture of Timothy M Cox
    Role: Principal Investigator
    Affiliation(s): Department of Medicine
    Research Summary:
    We seek to understand the molecular causation of inborn errors of metabolism and to improve their outcome – conducting therapeutic research principally in the field of lysosomal disorders – with special reference to those which affect the brain. ... Read more
  • Profile picture of Priscilla Day
    Role: Post Doctoral
    Affiliation(s): Department of Physiology, Development and Neuroscience
    Research Summary:
    I am interested in understanding the role of nutrition metabolism and mitochondrial function in developmental plasticity and the predisposition to metabolic syndrome in adulthood. I am also interested in the coordination between metabolism and cell... Read more
  • Profile picture of Laura Dearden
    Role: Post Doctoral
    Affiliation(s): Metabolic Research Laboratories
    Research Summary:
    I am investigating how developing in an environment of maternal obesity and gestational diabetes alters development of the hypothalamus in offspring, and how disrupted hypothalamic development underpins the changes in feeding behaviour that ultimatel... Read more
  • Profile picture of Chaitanya Dingare
    Role: Post Doctoral
    Affiliation(s): Department of Genetics
    Research Summary:
    Department of Genetics
  • Profile picture of Anne Ferguson-Smith
    Role: Principal Investigator
    Affiliation(s): Department of Genetics
    Research Summary:
    Our lab focuses on the molecular events governing pre- and post-natal mammalian development. Our research is directed towards investigating the developmental role of imprinted genes and the epigenetic mechanism(s) controlling their parental-origin sp... Read more
  • Profile picture of Denise Fernandez-Twinn
    Role: Post Doctoral
    Affiliation(s): Department of Clinical Biochemistry, Institute of Metabolic Science -Metabolic Research Laboratories
    Research Summary:
    Programmed changes in miRNA expression link early life nutrition to long-term health.  Specifically, my work has shown that miR-483-3p is up-regulated in adipose tissue from low birth-weight adult humans and pre-diabetic adult rats exposed to sub-op... Read more
  • Profile picture of Abigail Fowden
    Role: Principal Investigator
    Affiliation(s): Department of Physiology, Development and Neuroscience
    Research Summary:
    My research interests are in developmental physiology with particular emphasis on the metabolic and endocrine mechanisms controlling intrauterine development and its long term postnatal consequences. The research takes an integrated approach from the... Read more
  • Profile picture of Antonio Galvao
    Role: Post Doctoral
    Affiliation(s): The Babraham Institute
    Research Summary:
    My research programme will characterise changes in methylome and transcriptome of oocytes and early embryos from different mouse models for obesity and leptin signalling, using novel methods for studying epigenetics such as whole genome single cell ... Read more
  • Profile picture of Jinghua Gui
    Role: Post Doctoral
    Affiliation(s): Department of Genetics
    Research Summary:
    Department of Genetics
  • Profile picture of Ranna El Khairi
    Role: PhD Student
    Affiliation(s): Wellcome Trust Sanger Institute
    Research Summary:
    I am a Wellcome Trust Clinical Research Fellow undertaking a PhD under the supervision of Dr Ludovic Vallier. My project involves the use of human pluripotent stem cells (PSCs) to study the mechanisms involved in the pathogenesis of monogenic forms... Read more
  • Profile picture of Jorge Lopez-Tello
    Role: Post Doctoral
    Affiliation(s): Department of Physiology, Development and NeuroscienceNewton Royal Society Fellow
    Research Summary:
    During pregnancy, the mother must adapt metabolically to support offspring growth. Failures in maternal adaptation can result in pregnancy complications like gestational diabetes, which is a risk factor for type-2 diabetes in later motherhood. The pl... Read more
  • Profile picture of Florian Merkle
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    My laboratory uses human stem cell-derived hypothalamic neurones to study the genetic and environmental factors that contribute to obesity. Many genetic variants associated with obesity are expressed in the brain, particularly in hypothalamic neurone... Read more
  • Profile picture of Ken Ong
    Role: Principal Investigator
    Affiliation(s): Department of Medicine, Department of Paediatrics, MRC Epidemiology Unit
    Research Summary:
    Ken Ong leads the Unit’s Growth and Development programme. His research identified rapid postnatal growth, weight gain and reproductive timing as determinants of, and also potential targets for the prevention of, childhood obesity, type 2 diabetes ... Read more
  • Profile picture of Susan Ozanne
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    Early Programming of Appetite, Type 2 Diabetes, Breast Cancer and Ageing The major focus of our research is to understand the mechanistic basis of the relationships between poor early growth and subsequent increased risk of type 2 diabetes, obesit... Read more
  • Profile picture of Clive Petry
    Role: Post Doctoral
    Affiliation(s): Department of Paediatrics
    Research Summary:
    I am a Senior Research Associate working in the Department of Paediatrics. My research is involved in trying to understand the mechanisms and consequences of the link between altered fetal growth and the future development of diseases such as gestati... Read more