• Profile picture of Dunja Aksentijevic
    Role: Other
    Affiliation(s): The Rayne Institute, BHF Centre of Research Excellence, Kings College London
    Research Summary:
    I am an associate lecturer in Cardiovascular Division at King's BHF Centre of Research Excellence with 8 years of cardiac metabolism scientific research experience (at the University of Oxford BHF Centre of Research Excellence, Prof Stefan Neubauer'... Read more
  • Profile picture of Kevin Brindle
    Role: Principal Investigator
    Affiliation(s): CRUK Cambridge Institute, Department of Biochemistry
    Research Summary:
    The primary aim of my laboratory is to develop clinically applicable imaging methods that can be used to detect early tumour responses to treatment. These could be used in early stage clinical trials of new drugs to get an indication of efficacy and... Read more
  • Profile picture of Timothy M Cox
    Role: Principal Investigator
    Affiliation(s): Department of Medicine
    Research Summary:
    We seek to understand the molecular causation of inborn errors of metabolism and to improve their outcome – conducting therapeutic research principally in the field of lysosomal disorders – with special reference to those which affect the brain. ... Read more
  • Profile picture of David Dunger
    Role: Principal Investigator
    Affiliation(s): Department of Paediatrics, Metabolic Research Laboratories
    Research Summary:
    Research Interests

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  • Profile picture of Mark Evans
    Role: Principal Investigator
    Affiliation(s): Department of Medicine, Metabolic Research Laboratories
    Research Summary:
    I am interested in (1) how brain detects changes in blood glucose and how this glucose-sensing interacts with peripheral metabolism (2) how defences against hypoglycaemia (low blood sugar) may become abnormal in diabetes (3) the short and long term e... Read more
  • Profile picture of I. Sadaf Farooqi
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry
    Research Summary:
    The long term goal of our research is to understand the molecular and physiological pathways involved in the regulation of human appetite and body weight. To this end, we use a number of complementary genetic strategies to study over 5,500 patients w... Read more
  • Profile picture of Fiona Gribble
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    Hormones from the gut are central to the control of appetite and insulin release. Drugs based on the gut hormone glucagon-like peptide-1 (GLP-1) have proved highly successful for treating type 2 diabetes, and also suppress food intake. In collaborati... Read more
  • Profile picture of Roman Hovorka
    Role: Principal Investigator
    Affiliation(s): Department of Paediatrics, Metabolic Research Laboratories
    Research Summary:
    Mathematical modeling to support diagnosis and treatment of metabolic diseases Our aim is to support the diagnosis and treatment of metabolic diseases using mathematical modeling techniques with particular focus on diabetes. We use existing and de... Read more
  • Profile picture of Andrew Jones
    Role: Post Doctoral
    Affiliation(s): Domainex
    Research Summary:
  • Profile picture of Jorge Lopez-Tello
    Role: Post Doctoral
    Affiliation(s): Department of Physiology, Development and NeuroscienceNewton Royal Society Fellow
    Research Summary:
    During pregnancy, the mother must adapt metabolically to support offspring growth. Failures in maternal adaptation can result in pregnancy complications like gestational diabetes, which is a risk factor for type-2 diabetes in later motherhood. The pl... Read more
  • Profile picture of Karthik Nadendla
    Role: Post Doctoral
    Affiliation(s): Department of Chemistry
    Research Summary:
    Department of Chemistry
  • Profile picture of Antonella Napolitano
    Role: Principal Investigator
    Affiliation(s): GSK
    Research Summary:
  • Profile picture of Stephen O'Rahilly
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    I have a long-standing interest in the aetiology and pathophysiology of human metabolic and endocrine disease and how such information might be used to improve diagnosis, prognostication, therapy and prevention. I have a long-standing, close, collabo... Read more
  • Profile picture of Hiran A. Prag
    Role: Post Doctoral
    Affiliation(s): MRC Mitochondrial Biology Unit
    Research Summary:
    I am currently interested in the role of mitochondria in ischaemia/reperfusion (I/R) injury, occurring in heart attack, stroke and organ transplantation. In particular, I am interested in the role of the mitochondrial metabolite succinate and the rol... Read more
  • Profile picture of Frank Reimann
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    Intestinal hormone secretion and action The intestinal epithelium is scattered with enteroendocrine cells, which, although only accounting for less than 1% of this tissue, can be considered the biggest endocrine organ in the body. Some of the pept... Read more
  • Profile picture of Antonia Wierzbicki
    Role: Other
    Affiliation(s): Shimadzu UK
    Research Summary: