• Profile picture of Jelle van den Ameele
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Neurosciences, MRC Mitochondrial Biology Unit
    Research Summary:
    Department of Clinical Neurosciences, MRC Mitochondrial Biology Unit
  • Profile picture of Claudio Angione
    Role: Principal Investigator
    Affiliation(s): Computer Laboratory
    Research Summary:
  • Profile picture of Professor Margaret Ashcroft
    Role: Principal Investigator
    Affiliation(s): Department of Medicine
    Research Summary:
    The main goal of the Ashcroft laboratory is to understand the key cellular mechanisms involved in hypoxia signalling and control of oxygenation. In particular, we have a strong interest in the hypoxia inducible factor (HIF) family of transcription fa... Read more
  • Profile picture of Clemence Blouet
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    My work focuses on the characterization of brain nutrient-sensing circuits implicated in the regulation of energy homeostasis. This research is done through 3 main axes: 1. the characterization of molecular mechanisms implicated in brain nutrie... Read more
  • Profile picture of Soren Brage
    Role: Principal Investigator
    Affiliation(s): MRC Epidemiology Unit
    Research Summary:
    Physical activity and fitness are key factors in obesity and metabolic disease, as well as in many other chronic diseases. However, these associations are still not completely clear. A major reason for this is that physical activity is difficult to m... Read more
  • Profile picture of Kevin Brindle
    Role: Principal Investigator
    Affiliation(s): CRUK Cambridge Institute, Department of Biochemistry
    Research Summary:
    The primary aim of my laboratory is to develop clinically applicable imaging methods that can be used to detect early tumour responses to treatment. These could be used in early stage clinical trials of new drugs to get an indication of efficacy and... Read more
  • Profile picture of Olivia Casanueva
    Role: Principal Investigator
    Affiliation(s): The Babraham Institute
    Research Summary:
    Aging can be described as the steady decline in overall function, and increase in incidence of age-related diseases, over an organism’s lifetime. Remarkably, this process can be radically delayed through the reduction of dietary intake without maln... Read more
  • Profile picture of Havovi Chichger
    Role: Principal Investigator
    Affiliation(s): Cambridge Cardiovascular Research; Anglia Ruskin University
    Research Summary:
  • Profile picture of Anthony Coll
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    My work focuses on the molecular mechanism controlling food intake and energy expenditure. Our current understanding of the central control of appetite has relied heavily upon mouse models and I continue to combine murine genetics and whole animal ph... Read more
  • Profile picture of Matthew Collins
    Role: Principal Investigator
    Affiliation(s): Department of Archaeology
    Research Summary:
  • Profile picture of Miguel Constância
    Role: Principal Investigator
    Affiliation(s): Metabolic Research LaboratoriesDepartment of Obstetrics and Gynaecology
    Research Summary:
    Epigenetics is an exciting and rapidly moving field that impacts basic biomedical research and clinical medicine. Epigenetic mechanisms such as DNA methylation, histone modifications and non-coding RNAs provide dynamic, heritable and reversible ways ... Read more
  • Profile picture of Timothy M Cox
    Role: Principal Investigator
    Affiliation(s): Department of Medicine
    Research Summary:
    We seek to understand the molecular causation of inborn errors of metabolism and to improve their outcome – conducting therapeutic research principally in the field of lysosomal disorders – with special reference to those which affect the brain. ... Read more
  • Profile picture of Gabrielle Davidson
    Role: Principal Investigator
    Affiliation(s): Cambridge Department of Psychology
    Research Summary:
    I study the causes and consequences of individual differences in cognition and behaviour in wild birds. I employ a mixture of field-based research using advanced automated data collection devices, cognitive assays in captivity and molecular technique... Read more
  • Profile picture of David Dunger
    Role: Principal Investigator
    Affiliation(s): Department of Paediatrics, Metabolic Research Laboratories
    Research Summary:
    Research Interests

    Read more

  • Profile picture of Mark Evans
    Role: Principal Investigator
    Affiliation(s): Department of Medicine, Metabolic Research Laboratories
    Research Summary:
    I am interested in (1) how brain detects changes in blood glucose and how this glucose-sensing interacts with peripheral metabolism (2) how defences against hypoglycaemia (low blood sugar) may become abnormal in diabetes (3) the short and long term e... Read more
  • Profile picture of I. Sadaf Farooqi
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry
    Research Summary:
    The long term goal of our research is to understand the molecular and physiological pathways involved in the regulation of human appetite and body weight. To this end, we use a number of complementary genetic strategies to study over 5,500 patients w... Read more
  • Profile picture of Daniel Fazakerley
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry, Institute of Metabolic Science -Metabolic Research Laboratories
    Research Summary:
    The Fazakerley group is interested in understanding the molecular details of insulin-stimulated glucose transport, and how this process breaks down in disease. One of the ways in which insulin lowers blood glucose is through stimulating gluco... Read more
  • Profile picture of Anne Ferguson-Smith
    Role: Principal Investigator
    Affiliation(s): Department of Genetics
    Research Summary:
    Our lab focuses on the molecular events governing pre- and post-natal mammalian development. Our research is directed towards investigating the developmental role of imprinted genes and the epigenetic mechanism(s) controlling their parental-origin sp... Read more
  • Profile picture of Paul Fletcher
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Neurosciences
    Research Summary:
    My work focuses on questions related to the brain’s reward systems and to how characterisation of these systems, and the complex behaviours that they support, may form a key part of understanding the growing population-wide vulnerability to health-... Read more
  • Profile picture of Abigail Fowden
    Role: Principal Investigator
    Affiliation(s): Department of Physiology, Development and Neuroscience
    Research Summary:
    My research interests are in developmental physiology with particular emphasis on the metabolic and endocrine mechanisms controlling intrauterine development and its long term postnatal consequences. The research takes an integrated approach from the... Read more