• Profile picture of Professor Margaret Ashcroft
    Role: Principal Investigator
    Affiliation(s): Department of Medicine
    Research Summary:
    The main goal of the Ashcroft laboratory is to understand the key cellular mechanisms involved in hypoxia signalling and control of oxygenation. In particular, we have a strong interest in the hypoxia inducible factor (HIF) family of transcription fa... Read more
  • Profile picture of Vian Azzu
    Role: Other
    Affiliation(s): Institute of Metabolic Science -Metabolic Research LaboratoriesCambridge University Hospitals, Norfolk and Norwich University Hospital
    Research Summary:
    Institute of Metabolic Science -Metabolic Research Laboratories
  • Profile picture of BRIDGET BANNERMAN
    Role: Post Doctoral
    Affiliation(s): Department of Medicine
    Research Summary:
    Department of Medicine
  • Profile picture of Kevin Brindle
    Role: Principal Investigator
    Affiliation(s): CRUK Cambridge Institute, Department of Biochemistry
    Research Summary:
    The primary aim of my laboratory is to develop clinically applicable imaging methods that can be used to detect early tumour responses to treatment. These could be used in early stage clinical trials of new drugs to get an indication of efficacy and... Read more
  • Profile picture of Paola Caruso
    Role: Post Doctoral
    Affiliation(s): Department of Medicine
    Research Summary:
    My main interest is to investigate the role of specific miRNAs in the metabolic abnormalities identified in pulmonary arterial hypertension (PAH), a rare but fatal disease characterised by profound vascular abnormalities in the peripheral arteries of... Read more
  • Profile picture of Zhenghao Chen
    Role: PhD Student
    Affiliation(s): Univerisity Medical Center Amsterdam, University of Amsterdam
    Research Summary:
  • Profile picture of Tinh-Hai Collet
    Role: Post Doctoral
    Affiliation(s): Department of Clinical Biochemistry
    Research Summary:
    Department of Clinical Biochemistry
  • Profile picture of Timothy M Cox
    Role: Principal Investigator
    Affiliation(s): Department of Medicine
    Research Summary:
    We seek to understand the molecular causation of inborn errors of metabolism and to improve their outcome – conducting therapeutic research principally in the field of lysosomal disorders – with special reference to those which affect the brain. ... Read more
  • Profile picture of Jeremy Deuel
    Role: Post Doctoral
    Affiliation(s): Cambridge Stem Cell Institute and Department of Haematology
    Research Summary:
    I am studying the role of Stat5b in the pathogenesis of myeloproliferative neoplasms (MPN) such as Polycythemia Vera. The three most common driver mutations of MPN are JAK2-V617F, CALR-mutations and mutations of the thrombopoietin receptor MPL. It ha... Read more
  • Profile picture of I. Sadaf Farooqi
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry
    Research Summary:
    The long term goal of our research is to understand the molecular and physiological pathways involved in the regulation of human appetite and body weight. To this end, we use a number of complementary genetic strategies to study over 5,500 patients w... Read more
  • Profile picture of Fiona Gribble
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    Hormones from the gut are central to the control of appetite and insulin release. Drugs based on the gut hormone glucagon-like peptide-1 (GLP-1) have proved highly successful for treating type 2 diabetes, and also suppress food intake. In collaborati... Read more
  • Profile picture of Timo Haschler
    Role: Other
    Affiliation(s): AstraZeneca
    Research Summary:
  • Profile picture of Christoph Hess
    Role: Principal Investigator
    Affiliation(s): Department of Medicine
    Research Summary:
    The metabolic repertoire of immune cells – which encompasses metabolic enzymes/pathways, the available nutrient sensors and metabolic checkpoint kinases, and the epigenetic programming of metabolic genes – enables and modulates specific immune fu... Read more
  • Profile picture of Isabel Huang-Doran
    Role: Post Doctoral
    Affiliation(s): Metabolic Research Laboratories
    Research Summary:
    Metabolic Research Laboratories
  • Profile picture of Julia Keogh
    Role: Other
    Affiliation(s):
    Research Summary:
  • Profile picture of Tomasz Kostrzewski
    Role: Principal Investigator
    Affiliation(s): CN Bio Innovations
    Research Summary:
  • Profile picture of Jorge Lopez-Tello
    Role: Post Doctoral
    Affiliation(s): Department of Physiology, Development and NeuroscienceNewton Royal Society Fellow
    Research Summary:
    During pregnancy, the mother must adapt metabolically to support offspring growth. Failures in maternal adaptation can result in pregnancy complications like gestational diabetes, which is a risk factor for type-2 diabetes in later motherhood. The pl... Read more
  • Profile picture of Madhuri Manohar
    Role: PhD Student
    Affiliation(s): Department of Chemical Engineering and Biotechnology
    Research Summary:
  • Profile picture of Ines Horvat Menih
    Role: PhD Student
    Affiliation(s): CRUK Cambridge InstituteDepartment of Radiology
    Research Summary:
    CRUK Cambridge Institute
  • Profile picture of Jacek Mokrosinski
    Role: Post Doctoral
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    My main research interests and speciality lie in the field of molecular in vitro pharmacology of 7-transmembrane G-protein coupled receptors (GPCR). I am studying structural and functional properties of rhodopsin-like (class A) GPCRs. I am a postdoct... Read more