• Profile picture of Miguel Constância
    Role: Principal Investigator
    Affiliation(s): Metabolic Research LaboratoriesDepartment of Obstetrics and Gynaecology
    Research Summary:
    Epigenetics is an exciting and rapidly moving field that impacts basic biomedical research and clinical medicine. Epigenetic mechanisms such as DNA methylation, histone modifications and non-coding RNAs provide dynamic, heritable and reversible ways ... Read more
  • Profile picture of Timothy M Cox
    Role: Principal Investigator
    Affiliation(s): Department of Medicine
    Research Summary:
    We seek to understand the molecular causation of inborn errors of metabolism and to improve their outcome – conducting therapeutic research principally in the field of lysosomal disorders – with special reference to those which affect the brain. ... Read more
  • Profile picture of Francesco Cucco
    Role: Post Doctoral
    Affiliation(s): Department of Pathology
    Research Summary:
  • Profile picture of Priscilla Day
    Role: Post Doctoral
    Affiliation(s): Department of Physiology, Development and Neuroscience
    Research Summary:
    I am interested in understanding the role of nutrition metabolism and mitochondrial function in developmental plasticity and the predisposition to metabolic syndrome in adulthood. I am also interested in the coordination between metabolism and cell... Read more
  • Profile picture of Jeremy Deuel
    Role: Post Doctoral
    Affiliation(s): Cambridge Stem Cell Institute and Department of Haematology
    Research Summary:
    I am studying the role of Stat5b in the pathogenesis of myeloproliferative neoplasms (MPN) such as Polycythemia Vera. The three most common driver mutations of MPN are JAK2-V617F, CALR-mutations and mutations of the thrombopoietin receptor MPL. It ha... Read more
  • Profile picture of Chaitanya Dingare
    Role: Post Doctoral
    Affiliation(s): Department of Genetics
    Research Summary:
    Department of Genetics
  • Profile picture of Elves Duarte
    Role: Post Doctoral
    Affiliation(s): Department of Genetics
    Research Summary:
    I am interested in studying the interaction between insects and microorganisms, namely between mosquitoes and the intracellular bacterium Wolbachia. The ultimate goal is to establish Wolbachia as a self-sustainable approach to control mosquito-borne ... Read more
  • Profile picture of Joao Duarte
    Role: Post Doctoral
    Affiliation(s): Department of Radiology, School of Clinical Sciences
    Research Summary:
  • Profile picture of David Dunger
    Role: Principal Investigator
    Affiliation(s): Department of Paediatrics, Metabolic Research Laboratories
    Research Summary:
    Research Interests

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  • Profile picture of Mark Evans
    Role: Principal Investigator
    Affiliation(s): Department of Medicine, Metabolic Research Laboratories
    Research Summary:
    I am interested in (1) how brain detects changes in blood glucose and how this glucose-sensing interacts with peripheral metabolism (2) how defences against hypoglycaemia (low blood sugar) may become abnormal in diabetes (3) the short and long term e... Read more
  • Profile picture of I. Sadaf Farooqi
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry
    Research Summary:
    The long term goal of our research is to understand the molecular and physiological pathways involved in the regulation of human appetite and body weight. To this end, we use a number of complementary genetic strategies to study over 5,500 patients w... Read more
  • Profile picture of Daniel Fazakerley
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry, Institute of Metabolic Science -Metabolic Research Laboratories
    Research Summary:
    The Fazakerley group is interested in understanding the molecular details of insulin-stimulated glucose transport, and how this process breaks down in disease. One of the ways in which insulin lowers blood glucose is through stimulating gluco... Read more
  • Profile picture of Anne Ferguson-Smith
    Role: Principal Investigator
    Affiliation(s): Department of Genetics
    Research Summary:
    Our lab focuses on the molecular events governing pre- and post-natal mammalian development. Our research is directed towards investigating the developmental role of imprinted genes and the epigenetic mechanism(s) controlling their parental-origin sp... Read more
  • Profile picture of Denise Fernandez-Twinn
    Role: Post Doctoral
    Affiliation(s): Department of Clinical Biochemistry, IMS -Metabolic Research Laboratories
    Research Summary:
    Programmed changes in miRNA expression link early life nutrition to long-term health.  Specifically, my work has shown that miR-483-3p is up-regulated in adipose tissue from low birth-weight adult humans and pre-diabetic adult rats exposed to sub-op... Read more
  • Profile picture of Elizabeth Figueroa-Juarez
    Role: PhD Student
    Affiliation(s):
    Research Summary:
  • Profile picture of Rachel Foreman
    Role: PhD Student
    Affiliation(s):
    Research Summary:
  • Profile picture of Fiona Gribble
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    Hormones from the gut are central to the control of appetite and insulin release. Drugs based on the gut hormone glucagon-like peptide-1 (GLP-1) have proved highly successful for treating type 2 diabetes, and also suppress food intake. In collaborati... Read more
  • Profile picture of John Griffiths
    Role:
    Affiliation(s): CRUK Cambridge Institute
    Research Summary:
    CRUK Cambridge Institute
  • Profile picture of Afreen Haider
    Role: Post Doctoral
    Affiliation(s):
    Research Summary:
    A biochemist by training, I am interested in understanding the cellular and physiological regulation of human metabolic health with a long-term goal of contributing in translational research. My PhD work focused on identifying anti-malarial 'druggabl... Read more
  • Profile picture of Eric Harshfield
    Role: Post Doctoral
    Affiliation(s): Department of Clinical Neurosciences
    Research Summary:
    I am a chronic disease and genetic epidemiologist with an interest in identifying novel causal pathways and new therapeutic targets for reducing risk of chronic diseases. Since March 2018, I have been working as a Postdoctoral Research Associate in t... Read more