• Profile picture of Roman Hovorka
    Role: Principal Investigator
    Affiliation(s): Department of Paediatrics, Metabolic Research Laboratories
    Research Summary:
    Mathematical modeling to support diagnosis and treatment of metabolic diseases Our aim is to support the diagnosis and treatment of metabolic diseases using mathematical modeling techniques with particular focus on diabetes. We use existing and de... Read more
  • Profile picture of Isabel Huang-Doran
    Role: Post Doctoral
    Affiliation(s): Metabolic Research Laboratories
    Research Summary:
    Metabolic Research Laboratories
  • Profile picture of Camilla Ingvorsen
    Role: Post Doctoral
    Affiliation(s): Metabolic Research Laboratories, Wellcome Trust Sanger Institute
    Research Summary:
    I received my PhD from the Technical University of Denmark in 2013, where I studied the effect of a high fat diet during pregnancy in rodents and the risk of obesity, metabolic dysfunction and obesity-induced inflammation in the young and adult offsp... Read more
  • Profile picture of Dr Benjamin Jenkins
    Role: Post Doctoral
    Affiliation(s): Cambridge Institute for Medical Research, Department of Biochemistry, Institute of Metabolic Science -Metabolic Research Laboratories, Wellcome Trust Sanger Institute
    Research Summary:
    I am currently in a post-doc role in the NIHR Core Metabolomics and Lipidomics Laboratory Wellcome-MRC Institute of Metabolic Science as an analytical chemist. My role involves exclusively mass spectrometry based detection of small molecules with sev... Read more
  • Profile picture of Richard Kay
    Role: Post Doctoral
    Affiliation(s): Metabolic Research Laboratories
    Research Summary:
    15 years experience at a contract research organisation developing LC-MS methods for quantifying peptides and proteins from pre-clinical and clinical trials supporting biopharmaceutical drug development. Extensive use of triple quadrupole instruments... Read more
  • Profile picture of Abigail Kerridge
    Role: Other
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    Department of Clinical Biochemistry, Metabolic Research Laboratories
  • Profile picture of Sara Kohnke
    Role: PhD Student
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    Department of Clinical Biochemistry, Metabolic Research Laboratories
  • Profile picture of Jennie Leggat
    Role: PhD Student
    Affiliation(s): Department of Clinical Biochemistry, Department of Medicine, IMS -Metabolic Research Laboratories
    Research Summary:

    Non-alcoholic fatty liver disease (NAFLD) is a spectral condition of excessive hepatic lipid accumulation. It is already the most prevalent hepatic pathology... Read more

  • Profile picture of Chris Lelliott
    Role: Other
    Affiliation(s): Institute of Metabolic Science -Metabolic Research Laboratories
    Research Summary:
    I am the Director of the Disease Model Core at the Institute of Metabolic Science, Cambridge University. The team aims to provide experimental and operational support for researchers who use mouse models in their research on metabolic systems.  T... Read more
  • Profile picture of Jo Lewis
    Role: Post Doctoral
    Affiliation(s): Metabolic Research Laboratories
    Research Summary:
    Metabolic Research Laboratories
  • Profile picture of Van Lu
    Role: Post Doctoral
    Affiliation(s): Department of Clinical Biochemistry, IMS -Metabolic Research Laboratories
    Research Summary:
    I am interested in elucidating the mechanisms governing hormonal release particularly hormones from endocrine cells lining the gut epithelium, the enteroendocrine cells. I am also interested in understanding how enteroendocrine cells communicate with... Read more
  • Profile picture of Florian Merkle
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    My laboratory uses human stem cell-derived hypothalamic neurones to study the genetic and environmental factors that contribute to obesity. Many genetic variants associated with obesity are expressed in the brain, particularly in hypothalamic neurone... Read more
  • Profile picture of Emily Miedzybrodzka
    Role: PhD Student
    Affiliation(s): IMS -Metabolic Research Laboratories
    Research Summary:
    IMS -Metabolic Research Laboratories
  • Profile picture of Nikolay Milev
    Role: PhD Student
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    Circadian timekeeping is a fundamental characteristic of almost all living cells and is essential for coordinated physiology. Traditionally, the mechanism of the circadian clock has centered on the transcriptional oscillations of a set of core clock ... Read more
  • Profile picture of Jacek Mokrosinski
    Role: Post Doctoral
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    My main research interests and speciality lie in the field of molecular in vitro pharmacology of 7-transmembrane G-protein coupled receptors (GPCR). I am studying structural and functional properties of rhodopsin-like (class A) GPCRs. I am a postdoct... Read more
  • Profile picture of Stephen O'Rahilly
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    I have a long-standing interest in the aetiology and pathophysiology of human metabolic and endocrine disease and how such information might be used to improve diagnosis, prognostication, therapy and prevention. I have a long-standing, close, collabo... Read more
  • Profile picture of Susan Ozanne
    Role: Principal Investigator
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    Early Programming of Appetite, Type 2 Diabetes, Breast Cancer and Ageing The major focus of our research is to understand the mechanistic basis of the relationships between poor early growth and subsequent increased risk of type 2 diabetes, obesit... Read more
  • Profile picture of Lucas Pantaleao
    Role: Post Doctoral
    Affiliation(s): IMS -Metabolic Research Laboratories
    Research Summary:
    I am a developmental biologist with particular interest in learning the underlying mechanisms leading to intergenerational changes in mammalian phenotype in response to developmental challenges. More than observing the physiological consequences of... Read more
  • Profile picture of Victoria Parker
    Role: PhD Student
    Affiliation(s): Metabolic Research Laboratories
    Research Summary:
    Metabolic Research Laboratories
  • Profile picture of Satish Patel
    Role: Post Doctoral
    Affiliation(s): Department of Clinical Biochemistry, Metabolic Research Laboratories
    Research Summary:
    Our work is focussed in understanding the molecular mechanisms and fundamental biology of certain lipid droplet proteins that are mutated in the rare inherited human disease of lipodystrophy. We are using several approaches to investigate this: Cand... Read more