I am a research associate working in the Institute of Metabolic Science with Fiona Gribble and Frank Reimann. My work focuses on characterising the central targets of incretin hormones.
Transcriptomic profiling of pancreatic alpha, beta and delta cell populations identifies delta cells as a principal target for ghrelin in mouse islets.
A Transcriptome-Led Exploration of Molecular Mechanisms Regulating Somatostatin-Producing D-Cells in the Gastric Epithelium.
Inhibition of the malate-aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion.
Reversible changes in pancreatic islet structure and function produced by elevated blood glucose.
Insulin-like peptide 5 is an orexigenic gastrointestinal hormone.
Identification and characterization of GLP-1 receptor-expressing cells using a new transgenic mouse model.
Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion.