Member Listing


Hood Thabit


Department of Clinical Biochemistry, Department of Medicine, Metabolic Research Laboratories




PhD Student

Research Summary

I am a qualified diabetologist with research and clinical interests in the field of medical devices and closed-loop technology. My PhD is in the development and application of an artificial pancreas (closed-loop insulin delivery) system for use in the clinical environment in patients with type 1 and type 2 diabetes mellitus


Clinical Trials, Endocrinology, Medical Devices and Therapeutics

Selected Publications

1. Thabit H, Elleri D, Leelarathna L, Allen JM, Lubina-Solomon A, Stadler M, Walkinshaw E, Iqbal A, Choudhary P, Wilinska ME, Barnard KD, Heller SR, Amiel SA, Evans ML, Dunger DB, Hovorka R. Unsupervised home use of overnight closed-loop system over 3 to 4 weeks – Pooled analysis of randomized controlled studies in adults and adolescents with type 1 diabetes. Diabetes Obes Metab. 2014 Dec 10

2. Thabit H, Lubina-Solomon A, Stadler M, Leelarathna L, Walkinshaw E, Pernet A, Allen JM, Iqbal A, Choudhary P, Kumareswaran K, Nodale M, Nisbet C, Wilinska ME, Barnard KD, Dunger DB, Heller SR, Amiel SA, Evans ML, Hovorka R. Home use of closed loop insulin delivery improves overnight glucose control in adults with type 1 diabetes: A four-week multicentre randomised crossover study. Lancet Diabetes Endocr 2014 Sep;2(9):701-9

3. Hovorka R, Elleri D, Thabit H, Allen JM, Leelarathna L, El-Khairi R, Kumareswaran K, Caldwell K, Calhoun P, Kollman C, Murphy HR, Acerini CL, Wilinska ME, Nodale M, Dunger DB Overnight closed loop insulin delivery in young people with type 1 diabetes: a free-living randomised clinical trial. Diabetes Care. 2014 May;37(5):1204-11

4. Ruan Y, Thabit H, Kumareswaran K, Hovorka R. Pharmacokinetics of insulin lispro in type 2 diabetes during closed loop insulin delivery. Comput Methods Program Biomed 2014 Nov;117(2):298-307

5. Leelarathna L, Dellweg S, Mader JK, Allen JM, Benesch C, Doll W, Ellmerer M, Hartnell S, Heinemann L, Kojzar H, Michalewski L, Nodale M, Thabit H, Wilinska ME, Pieber TR, Arnolds S, Evans ML, Hovorka R; AP@home Consortium. Day and night home closed-loop insulin delivery in adults with type 1 diabetes: three-center randomized crossover study. Diabetes Care. 2014 Jul;37(7):1931-7

6. Thabit H, Hovorka R. Glucose control in non-critically ill inpatients with diabetes: Towards closed-loop. Diabetes, Obesity and Metabolism. 2014 Jun;16(6):500-9

7. Thabit H, Hovorka R. Bringing closed loop home: Recent advances in closed loop insulin delivery. Curr Opin Endocrinol Diabetes Obes. 2014 Apr;21(2):95-101

8. Thabit H, Kumareswaran K, Haidar A, Leelarathna L, Caldwell K, Elleri D, Allen JM, Nodale M, Wilinska ME, Jackson NC, Umpleby AM, Evans ML, Hovorka R. Glucose turnover following replacement of usual therapy by insulin in insulin-naive type 2 diabetes subjects. J Clin Endo Metab 2014, Feb 25

9. Leelarathna L, English SW, Thabit H, Caldwell K, Allen JM, Kumareswaran K, Wilinska ME, Nodale M, Mangat J, Evans ML, Burnstein R, Hovorka R. Feasibility of fully automated closed-loop glucose control utilizing continuous subcutaneous glucose measurements in critical illness: a randomised controlled trial. Crit Care. 2013 Jul 24;17(4):R159. Epub ahead of print

10. Kumareswaran K, Thabit H, Leelarathna L, Caldwell K, Elleri D, Allen JM, Nodale M, Wilinska ME, Evans ML, Hovorka R. Feasibility of closed-loop insulin delivery in type 2 diabetes: a randomised controlled study. Diabetes Care 2013 Sep 11