Member Listing

Name

Isabel Huang-Doran

Affiliation

Metabolic Research Laboratories

Title

Dr

Role

Post Doctoral

Expertise

Cell Biology, Endocrinology, Translational Medicine

Selected Publications

Extracellular Vesicles: Novel Mediators of Cell Communication In Metabolic Disease.
Huang-Doran I, Zhang CY, Vidal-Puig A.
Trends Endocrinol Metab. 2017 Jan;28(1):3-18. doi: 10.1016/j.tem.2016.10.003. Epub 2016 Oct 31. Review.
PMID: 27810172

Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations.
Huang-Doran I, Tomlinson P, Payne F, Gast A, Sleigh A, Bottomley W, Harris J, Daly A, Rocha N, Rudge S, Clark J, Kwok A, Romeo S, McCann E, Müksch B, Dattani M, Zucchini S, Wakelam M, Foukas LC, Savage DB, Murphy R, O’Rahilly S, Barroso I, Semple RK.
JCI Insight. 2016 Oct 20;1(17):e88766.
PMID: 27766312

Genetic Rodent Models of Obesity-Associated Ovarian Dysfunction and Subfertility: Insights into Polycystic Ovary Syndrome.
Huang-Doran I, Franks S.
Front Endocrinol (Lausanne). 2016 Jun 7;7:53. doi: 10.3389/fendo.2016.00053. eCollection 2016. Review.
PMID: 27375552

Truncation of POC1A associated with short stature and extreme insulin resistance.
Chen JH, Segni M, Payne F, Huang-Doran I, Sleigh A, Adams C; UK10K Consortium, Savage DB, O’Rahilly S, Semple RK, Barroso I.
J Mol Endocrinol. 2015 Oct;55(2):147-58. doi: 10.1530/JME-15-0090.

Genetic defects in human pericentrin are associated with severe insulin resistance and diabetes.
Huang-Doran I, Bicknell LS, Finucane FM, Rocha N, Porter KM, Tung YC, Szekeres F, Krook A, Nolan JJ, O’Driscoll M, Bober M, O’Rahilly S, Jackson AP, Semple RK; Majewski Osteodysplastic Primordial Dwarfism Study Group.
Diabetes. 2011 Mar;60(3):925-35. doi: 10.2337/db10-1334. Epub 2011 Jan 26.
PMID: 21270239

Modeling inherited metabolic disorders of the liver using human induced pluripotent stem cells.
Rashid ST, Corbineau S, Hannan N, Marciniak SJ, Miranda E, Alexander G, Huang-Doran I, Griffin J, Ahrlund-Richter L, Skepper J, Semple R, Weber A, Lomas DA, Vallier L.
J Clin Invest. 2010 Sep;120(9):3127-36. doi: 10.1172/JCI43122. Epub 2010 Aug 25.
PMID: 20739751