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Postdoc Masterclass: “Genetic screening of the human kinome identifies a cellular signalling network predictive of brain atrophy in Alzheimer’s disease & Circadian abnormality in Alzheimer’s disease: insights from animal models”
15th April 2015 @ 6:30 pm - 8:00 pmFree
The Masterclass is a series of lecture/discussion forum presented by postdocs that provides unique opportunities for researchers/students in the biological sciences to:
• Share and discuss current hot topics in research fields.
• Present and discuss new cutting edge techniques, skills and tools being used in laboratories.
• Get together and discuss possible collaborations between and across laboratories.
• Learn about less familiar subject areas.
• Network and make friends across laboratories and departments.
• Promote university facilities and resources.
• With free pizza, beer, and wine
All (students, P.I.s, technicians etc.) are welcome!
Cellular signalling and circadian abnormality in Alzheimer’s disease
“Genetic screening of the human kinome identifies a cellular signalling network predictive of brain atrophy in Alzheimer’s disease” (Becky Inkster) Searching for gene variants that influence brain atrophy in Alzheimer’s disease is highly warranted; however, conventional genome-wide approaches have limited statistical power and fail to incorporate information about intrinsic biological relationships. The speaker will present new unpublished findings of a genetic network of kinases that putatively represent a set of functionally diverse genetic factors that relate to, and possibly predict, AD neurodegeneration.
“Circadian abnormality in Alzheimer’s disease: insights from animal models” (Ko-Fan Chen) Circadian abnormality, such as sleep fragmentation and disruption in rest/activity cycle, has been observed in various neurodegenerative disorders including Alzheimer’s disease (AD). The speaker will summarise circadian behavioural characteristics in AD and highlight the technical advances in measuring sleep and circadian behaviour in the related murine and fly models.
- Becky Inkster (Dept Psychiatry) & Ko-Fan Chen (Dept Genetics)
- Wednesday 15 April 2015, 18:30–20:00
- Gurdon Institute Tea Room.