Wednesday 16 January

08:45	**Registration opens**
09:30	Patrick Maxwell, University of Cambridge	Welcome from the Regius Professor of Physic and Head of the School of Clinical Medicine
09:40	Session 1: Epigenetic responses to metabolic / environmental changes
	Paolo Sassone-Corsi, University of California	The epigenetic language of circadian metabolism (KEYNOTE lecture)
	Jane Mellor, Univeristy of Oxford	Deconstructing the relationship between metabolism, chromatin and gene expression in the yeast metabolic cycle
	**Break and exhibition**
	Andrew Pospisilik, Van Andel Research institute and Max Planck Institute of Immunobiology and Epigenetics	Epigenetic contributions to metabolic disease heterogeneity
	Marcus Buschbeck, Josep Carreras Leukaemia Research institute	Short talk: Histone variants link metabolism to 3D chromatin architecture
12:30	Poster previews
12:45	**Lunch, optional sessions and posters**
15:10	Session 2: Metabolic control of epigenetic pathways
	Wolfgang Fischle, KAUST	Lipid precursors and lipids in chromatin regulation
	Kathryn Wellen, University of Pennsylvania	Acetyl-CoA metabolism and chromatin regulation
	Mattia Zhaghi, Vita-Salute San Raffaele university	Short talk: SETD5, a new connection between epigenetic & mitochondrial function
	**Break and exhibition**
	Thomas Carell, LMU	Title TBC
	Andreas Ladurner. LMU	Allosteric activation of a chromatin remodelling oncogene by NAD metabolites
18:00	Day 1 close
18:45	Drinks reception and conference dinner at Selwyn College

 

Thursday 17 January

09:05	Session 3: Physiological effects on the epigenome
	Erica Watson, University of Cambridge	How your grandparents’ sins affect your health
	Marika Charalambous, KCL	Genomic Imprinting – adiposity and pregnancy
	Alice Taylor, University of Cambridge	Short talk: Methionine metabolism impacts maintenance of AML with chromatin regulation
	**Break and exhibition**
	Cecilia Lindgren, University of Oxford	Epigenomics of common obesity
	Olivia Casaneueva, Babraham Institute	Variability in neuronal heat shock responses causes heterogeneity in fat metabolism across individual worms
	Simona Pedrotti, San Raffaele Hospital	Short talk: The histone methyltransferases Suv420h regulate PPAR-γ and energy expenditure in response to environmental stimuli
12:00	**Lunch and optional sessions**
13:25	Session 4: Metabolism and epigenetics in disease
	Judith Favier, INSERM	Uncoupled effects of TET inhibition and hypoxia in SDH-deficient cells
	Sevin Turcan, National Centre for Tumor Diseases, Heidelberg	The impact of IDH1 mutation on the glioma epigenome
	**Break and exhibition**
	Jason Locasale, Duke University	Diet, cancer and epigenetics
	Brian Huntly, University of Cambridge	Transcriptional and metabolic alterations during leukaemia evolution
15:50	Prof Sir Steve O’Rahilly, University of Cambridge                                    Prizes and closing remarks
16:00	Close

 

In addition to our plenary sessions the conference will offer an excellent opportunity to meet scientists outside your usual area of study and to think more broadly about your research. As well as plenty of time allowed for networking, to browse our exhibition and see posters presented by other participants, the programme will offer extra opportunities including:

• ‘Meet the speaker’ tables – dedicated time for conversations, over lunch, with some of our speakers
• Research talk from Rab Prinjha, VP Head of Epigenetics DPU, GSK
• Alternatives to academia. Careers session with Rab Prinjha, VP Head of Epigenetics DPU, GSK. Marc van der Schee, Head of Clinical at Owlstone Medical Ltd. and Daniel Ives, CEO of early stage startup Shift Bioscience.

Registered participants will be invited to sign up for one or more of our optional sessions shortly before the conference.

Who will be there?

This open meeting will draw experts and researchers who are new to the field from areas of study that are currently separated: cellular metabolism and epigenetics. It will embrace both interactions between small molecular metabolites with chromatin modifiers and clinically-relevant studies, bringing together researchers working on cancer, metabolic disease, chromatin regulation and diet.

Early Career Researchers are welcomed and encouraged to submit abstracts (please indicate interest when you REGISTER).

 

Our sponsors